Tropical Journal of Pharmaceutical Research

Review Article | OPEN ACCESS

Thin-Layer Chromatographic Analysis of Steroids: A Review

S A Bhawani¹ , O Sulaiman¹, R Hashim¹, Mohamad MN Ibrahim²

¹Division of Bio-Resource, Paper and Coatings Technology, School of Industrial Technology; ²School of Chemical Sciences, Universiti Sains Malaysia, 11800, Pulau Pinang, Malaysia.

For correspondence:- S Bhawani Email: sabhawani@gmail.com

Received: 15 November 2009 Accepted: 18 March 2010 Published: 24 June 2010

Citation: Bhawani SA, Sulaiman O, Hashim R, Ibrahim MM. Thin-Layer Chromatographic Analysis of Steroids: A Review. Trop J Pharm Res 2010; 9(3):301-313 doi: 10.4314/tjpr.v9i3.12

© 2010 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Thin layer chromatography has been used for the analysis of natural and synthetic steroids in various environmental materials. This review focuses mainly on steroid analysis in environmental materials such as pharmaceuticals, plant products and other biological specimens. The most widely investigated biological specimens are urine and blood plasma or serum. Various chromatographic systems useful for the identification; separation and quantification of surfactants are also reported in this review.

Keywords: Steroids; Thin layer chromatography; Environmental materials; Biological specimens